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Coronavirus: India drops convalescent plasma therapy from treatment protocol for adult patients

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India on Monday removed convalescent plasma therapy from the list of treatments prescribed for the management of adult coronavirus patients.

The revised guidelines, jointly issued by the Union health ministry, the Indian Council of Medical Research-Covid-19 National Task Force and the All India Institute of Medical Sciences, do not mention the use of convalescent plasma therapy.

Convalescent plasma therapy, an experimental treatment, involved giving the blood plasma of an individual who has recovered from the coronavirus infection to a patient in a serious condition. The antibodies in the recovered person’s plasma were expected to improve the condition of the patient requiring treatment.

The therapy was earlier allowed to be used for patients with moderate cases within seven days of the onset of the symptoms, and if a donor with high concentration of plasma was available, according to the Hindustan Times. The earlier guidelines clearly mentioned that the therapy had no use after seven days.

In November, the ICMR had issued an advisory against the “indiscriminate use” of convalescent plasma therapy as a treatment for the coronavirus infection. The advisory was based on the results of a randomised controlled trial among 464 Covid-19 patients with “moderate” symptoms across 39 hospitals in India.

The results showed that convalescent plasma therapy did not lead to a reduction in progression…

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